Leftover turkey casserole white lasagna on a plate

Leftover Turkey Casserole

Made with layers of turkey, noodles, squash, spinach, herbs, ricotta, and melted cheese, this leftover turkey casserole is a delicious variation on lasagna.

Course Main Course
Cuisine American, Italian
Keyword casserole, lasagna, leftovers, thanksgiving, turkey
Prep Time 15 minutes
Cook Time 45 minutes
Resting time 10 minutes
Total Time 1 hour
Servings 9
Calories 284 kcal
Author Pasta Fits


  • 1 tablespoon olive oil
  • 1 tablespoons butter
  • 1 onion finely chopped
  • 2 cloves garlic minced
  • 1 tablespoon chopped fresh sage
  • 2 teaspoons chopped fresh thyme
  • 3 tablespoons all-purpose flour
  • 3 1/2 cups 1% milk
  • 1/4 teaspoon salt
  • ground pepper
  • ground nutmeg
  • 8 ounces oven-ready lasagna noodles
  • 1 1/2 cups chopped cooked turkey breast
  • 4 cups chopped roasted butternut squash
  • 1/2 pound spinach steamed and squeezed dry
  • 1 cup part-skim ricotta cheese
  • 1 cup Italian cheese blend divided
  • 2 tablespoons chopped fresh parsley


  1. Heat oil and butter in skillet set over medium heat; cook onion, garlic, sage and thyme for about 5 minutes or until softened. Sprinkle flour over top; cook, stirring, for 1 minute.
  2. Gradually whisk in milk until smooth. Bring to boil, stirring constantly. Reduce heat to medium-low; simmer for about 10 minutes or until slightly thickened. Stir in salt, pepper and nutmeg.
  3. Preheat oven to 375°F. Spread 1/2 cup sauce evenly over bottom of greased 13- x 9-inch baking dish. Place 3 noodles over sauce. Spread 1 cup sauce, half of the turkey, butternut squash, spinach and ricotta over top; sprinkle with 1/3 cup cheese. Repeat layers. Place remaining 3 noodles over top; spread remaining sauce evenly over top and sprinkle with remaining cheese.
  4. Cover tightly with foil; bake for 30 minutes. Remove foil and bake for 15 to 20 minutes or until top is golden brown and filling is bubbling.
  5. Let stand for 10 minutes before serving. Sprinkle with fresh parsley before serving.
Nutrition Facts
Leftover Turkey Casserole
Amount Per Serving
Calories 284 Calories from Fat 81
% Daily Value*
Fat 9g14%
Saturated Fat 3g19%
Cholesterol 19mg6%
Sodium 214mg9%
Potassium 605mg17%
Carbohydrates 36g12%
Fiber 2g8%
Sugar 7g8%
Protein 14g28%
Vitamin A 9300IU186%
Vitamin C 21.3mg26%
Calcium 278mg28%
Iron 1.7mg9%
* Percent Daily Values are based on a 2000 calorie diet.